Dr. WEI-LUNG TSENG

◆Office: C3007

◆Laboratory: C3007

◆Telephone: +886-7-5252000 ext.3925

◆ Fax: +886-7-5254644

◆e-mail: tsengwl@mail.nsysu.edu.tw


Academic qualifications (beginning with bachelor's degree).

◇Ph.D., Analytical Chemistry, National Taiwan University(1997-2002)
◇B.S., Fu Jen Catholic University(1994-1997)


Details of employment and nature of duties.

Feb 2013-present: Professor, Department of Chemistry, National Sun Yat-sen University, Kaohsiung, Taiwan.
Nature of Duties: Teach graduate/undergraduate level courses; serve as advisor to students on their Masters and Doctoral dissertations; plan, direct, initiate, and conduct research in nanoparticle-related and separation-related research.

Feb 2009-Jan 2013: Associate Professor, Department of Chemistry, National Sun Yat-sen University, Kaohsiung, Taiwan.
Nature of Duties: Teach graduate/undergraduate level courses; serve as advisor to students on their Masters and Doctoral dissertations; plan, direct, initiate, and conduct research in nanoparticle-related and separation-related research.

Aug 2005-Jan 2009: Assistant Professor, Department of Chemistry, National Sun Yat-sen University, Kaohsiung, Taiwan.
Nature of Duties: Teach graduate/undergraduate level courses; serve as advisor to students on their Masters and Doctoral dissertations; plan, direct, initiate, and conduct research in nanoparticle-related and separation-related research.

Jan 2004-July 2005: Post-Doctoral Researcher, Department of Chemistry, National Taiwan University, Taipei, Taiwan.
Nature of Duties: Conduct research on the development of whole-column imaging capillary electrophoresis


Awards and/or other recognitions received (if any).

◇2008 Award for Outstanding Young Scholar, National Sun Yat-sen University
◇2009 Outstanding Young Investigator Award, the Chinese Chemical Society
◇2010 Mr. Wu Ta-you Memorial Award, National Science Council, Taiwan
◇2013 Award for Outstanding Scholar, National Sun Yat-sen University


Field of specialization.

  1. Capillary electrophoresis and its application
  2. Synthesis and application of metal nanoparticles/nanoclusters

Research experience

  1. 2005-to date.
    Wei-Lung Tseng is currently a Professor of Chemistry at National Sun Yet-sen University. He began his independent career as a member of the chemistry faculty at National Sun Yet-sen University in August of 2005. He has authored and co-authored more than 90 scientific publications. His research group is creating structures on metal nanoparticles for the development of colorimetric/fluorescent sensors and nanoparticle-related extraction system based molecular recognition and covalent bonding formation. Moreover, he devised a series of oligonucleotide-based sensors for selective and sensitive detection of heavy metal ions, anti-cancer drug, and single nucleotide polymorphisms. Current research includes:
    (i) the stabilization of gold nanoparticles and iron oxide nanoparticles with specific ligands for colorimetric/fluorescent detection of heavy metal ions, aminothiols, cyanide, hydrogen peroxide, and enzyme activity;
    (ii) protein-directed synthesis of highly fluorescent metal nanocluster and its application to the detection of Hg(II), CH3Hg(I), and glutathione;
    (iii) the combination of nanoparticle-based extraction and capillary electrophoresis for the determination of thiol-containing molecules, catechol-containing molecules, and environmental pollutants; and (iv) the development of oligonucleotide-related sensors based on non-base pairing interaction.
  2. 2004-2005.
    Wei-Lung Tseng joined the laboratory of Professor Huan-Tsung Chang (National Taiwan University, Taiwan) as a postdoctoral fellow. During this time, he developed whole-column imaging capillary electrophoresis for monitoring the migration of long DNA molecules, constructed a fluorescence and scattering microscopy system for determining the distribution and concentrations of glutathione within erythrocytes, and used a layer-by-layer assembly technique for fabricating multicolored-light-emitting films of CdSe@CdS and CdTe quantum dots.
  3. 1997-2002.
    Wei-Lung Tseng began his studies in Chemistry at National Taiwan University in 1997 and received his Ph.D. degree from National Taiwan University under the supervisor of Professor Huan-Tsung Chang in 2002. He explored how to use polymer solution to control electroosmotic flow in capillary electrophoresis. This finding opens a range of applications where polymer solutions are used to separate small molecules, DNA fragments, and proteins in the presence of electroosmotic flow. He won the "Dean's Award" Ph.D. degree in College of Science, National Taiwan University in 2002.

List of publications and/or patents of the nominee

2015
(109) Kumar, A. S. K., Jiang, S.-J.* and Tseng, W.-L.* “Effective adsorption of chromium (vi)/Cr (iii) from aqueous solution using ionic liquid functionalized multiwalled carbon nanotubes as a super sorbent”. J. Mater. A 2015, 3, 7044-7057

(108) Ke, C.-Y., Wu, Y.-T. and Tseng, W.-L.* “Fluorescein-5-isothiocyanate-conjugated protein-directed synthesis of gold nanoclusters for fluorescent ratiometric sensing of an enzyme–substrate system”. Biosens. & Bioelectron. 2015, 69, 46-53

(107) Chen, T.-H., Nieh, C.-C., Ya-Chen Shih, Y.-C., Ke, C.-Y. and Tseng, W.-L.* “Hydroxyl Radical-Induced Etching of Gold Nanoparticles to Oligomeric AuI-Thiolate Complexes”. RSC Adv. 2015, 5, 45158-45164.

(106) Lee, C.-Y. and Tseng, W.-L.* “Adenosine-Based Molecular Beacons for Fluorescent Detection of Oversulfated Chondroitin Sulfate Contaminants in Heparin without Enzyme Treatment.” Anal. Chem. 2015, 87, 5031-5035

(105) Lin, J.-H., Yu, C.-J., Yang, Y.-C. and Tseng, W.-L.* “Formation of Polydopamine Dots from Hydroxyl-Radical-Induced Degradation of Polydopamine Nanoparticles. Synthesis Mechanism and Application for Sensing Ferric Ions and H2O2”. Phys. Chem. Chem. Phys. 2015, 17, 15124-15130; selected as the inside of the cover)

(104) Su, H.-H., Chuang, L.-Y., Tseng, W.-L. and Lu, C.-Y.* “Micro-scale strategy to detect spermine and spermidine by MALDI–TOF MS in foods and identification of apoptosis-related proteins by nano-flow UPLC–MS/MS after treatment with spermine and spermidine”. J. Chromatogr. B 2015, 978-979, 131-137.

(103) Hung, S.-Y. and Tseng, W.-L.* “Tween 20-Stabilized Gold Nanoparticles Combined with Adenosine Triphosphate-BODIPY Conjugates for Fluorescence Detection of Adenosine with More Than 1000-Fold Selectivity. Anal. Chim. Acta 2015, 857, 64-70 (This article has been downloaded or viewed 387 times since publication.

(102) Lin, J.-H. and Tseng, W.-L.* “Ultrasensitive detection of target analyte-induced aggregation and growth of gold nanoparticles using laser-induced nanoparticle Rayleigh scattering”. Talanta, 2015, 132, 44-51. (This article has been downloaded or viewed 483 times since publication.

2014
(101) Shih, Y.-C., Ke, C.-Y. and Cheng-Ju Yu, C.-J. and Tseng, W.-L. “Combined Tween 20-Stabilized Gold Nanoparticles and Graphite Oxide-Fe3O4 Nanoparticle Composites for Rapid and Efficient Removal of Mercury Species in Environmental Water” ACS Materials & Interface 2014, 6, 17437-17445. (100) Lin, K.-C. Kuo, C.-Y. Nieh, C.-C. and Tseng, W.-L.* “Use of thymine-based molecular beacon for the construction of a NAND logic gate for Triplex DNA binders. RSC Adv., 2014, 4, 38389-38392

(99) Nieh, C.-C nd Tseng, W.-L.* “Thymine-Based Molecular Beacon for Sensing Enzyme Activity and Its Inhibition” Biosens & Bioelectronic (accepted)

(98) Ke, C.-Y., Chen, T.-H., Lu, L-C. and Tseng, W.-L.* “ Thiol-induced etching of luminescent gold nanoclusters: controlling lysozyme activity and sensing thimerosal” (RSC Advance, accepted)

(97) Yu, C.-J., Jiang J.-Y. and Tseng, W.-L.* “Lysozyme-Directed Synthesis of Platinum Nanoclusters as a Mimic Oxidase for Sensing Glutathione” (Nanoscale, accepted) (the inside of back cover)

(96) Huang, S.-Y. and Tseng, W.-L.* “A polyadenosine-coralyne complex as a novel fluorescent probe for the sensitive and selective detection of heparin in plasma.” Biosens. & Bioelectron. 2014, 57, 186-191.

(95) Lin, J.-H. and Tseng, W.-L.* “Design of two and three input molecular logic gates using non-Watson-Crick base pairing-based molecular beacons” Analyst 2014, 139, 1436-1441.

(94) Chen, T.-H. and Tseng, W.-L.* “Sinapinic acid-directed syntheis of gold nanocluster and its applicatin to quantitative matrix-assisted laser desorption/ionization mass spectrometry” Nanoscale, 2014, 6, 1347-1353 (the inside of back cover)

Non-corresponding author
(93) Lu, C.-Y., Su, H.-H., Chen, Y. –L.* and Tseng, W.-L. “Micro extraction to quantitate spermidine and spermine in human urine and blood by matrix-assisted laser desorption ionization time-of-flight mass spectrometry” J. Chromatogr. A, 2014, 1326, 1- 6.

2013
(92) Chen, T.-H. Lu, C.-Y. and Tseng, W. L.* “One-pot synthesis of two-sized metal clusters for ratiometric sensing of Hg2+” Talanta 2013, 117, 258-262

(91) Yu, C.-J., Wu, S.-M. and Tseng, W.-L.* “Magnetite Nanoparticle-Induced Fluorescence Quenching of Adenosine Triphosphate-BODIPY Conjugates: Application to Adenosine Triphosphate and Pyrophosphate Sensing” Anal. Chem. 2013, 85, 8559- 8565.

(90) Kuo, C. Y. and Tseng, W.-L.* “Adenosine-based molecular beacons as light-up probes for sensing heparin in plasma” Chem. Commun. 2013, 49, 4607-4609. (the inside of back cover)

(89) Lin, T.-H., Lu, C.-Y. and Tseng, W.-L.* “Selective enrichment of catecholamines using iron oxide nanoparticles followed by capillary electrophoresis” Electrophoresis 2013 34 297-303

(88) Lin, J.-H. and Tseng, W.-L.* “A method for fluorescence sensing of adenosine and alkaline phosphatase based on the inhibition of S-adenosylhomocysteine hydrolase activity” Biosens & Bioelectrons. 2013, 41 379-385

Non-corresponding author
(87) Chen, R.-C., Chuang, L. Y., Tseng, W.-L., Tyan, Y.-C. and Lu, C.-Y. “Determination of phosphoserine/threonine by nanoUPLC-MS/MS coupled with micro- scale labeling” Anal. Biochem. 2013, 433, 187-196.

2012
Corresponding author
(86) Lin, J.-H. and Tseng, W.-L.* “Gold nanoparticles for specific extraction and enrichment of bio-molecules and environmental pollutants” Review in Analytical Chemistry 2012, 31, 153-162 (invited review)

(85) Yeh, P.-R. and Tseng, W.-L.* “Human serum albumin-coated gold nanoparticles for selective extraction of lysozyme from real-world samples prior to capillary electrophoresis”. J. Chromatogr. A 2012, 1268, 166-172

(84) Liu, C.-H., Yu, C.-J. and Tseng, W.-L.* “Fluorescence assay of catecholamines based on the inhibition of peroxidase-like activity of Fe3O4 nanoparticles” Anal. Chim Acta 2012,745, 143-148.

(83) Liu, C.-Y. and Tseng, W.-L.* “Using polysorbate 40-stabilized gold nanoparticles in colorimetric assay of cyanogenic glycoside in plants” Anal. Methods 2012, 4, 2537

(82)* Lin, Y.-H. and Tseng, W.-L.* “A room-temperature adenosine-based molecular beacon for highly sensitive detection of nucleic acids” Chem. Comm. 2012, 48, 6262-6264.

(81)* Chen, T.-H. and Tseng, W.-L.* “Lysozyme type VI-stabilized Au8 clusters: synthesis mechanism and application for sensing of glutathione in a single drop of blood” Small, 2012, 8, 1912-1919.

(80) Wu, Z.-H., Lin, J.-H. and Tseng, W.-L.* “Oligonucleotide-Functionalized Silver Nanoparticle Extraction and Laser-Induced Fluorescence for Ultrasensitive Detection of Mercury(II) ion” Biosens. Bioelectron. 2012, 34, 185-190

(79) Lai, Y.-J. and Tseng, W.-L.* “Gold nanoparticle extraction followed by o- phthaldialdehyde derivatization for fluorescence sensing of different forms of homocysteine in plasma” Talanta 2012, 91, 103-109.

(78) Chen, C.-C., Tseng, W.-L.* and Hsieh, M.-M.* “Selective extraction of thiol- containing peptides in seawater using Tween 20-capped gold nanoparticles followed by capillary electrophoresis with laser-induced fluorescence”. J. Chromatogr. A 2012, 1220, 162-168.

Non-corresponding author
(77) Lee, H.-C., Chen, T.-H., Tseng, W.-L. and Lin, C.-H.* “Novel core etching technique of gold nanoparticles for colorimetric dopamine detection” Analyst 2012, 137, 5352-5357

(76) Chuang, C.H., Chuang, K. H., Wang, H. E., Roffler, S. R., Tzou, S. C., Cheng, T. C., Kao, C. H., Wu, S. Y., Tseng, W. L., Shiea, J., Wang, J. M. and Cheng, T. L.* In Vivo Positron Emission Tomography Imaging of Protease Activity by Generation of a Hydrophobic Product from a Noninhibitory Protease Substrate. Clin. Cancer Res. 2012, 18, 238-247.

(75) Chou, C.-H., Chuang, L.-Y., Tseng, W.-L. and Lu, C.-Y. “Characterization of protein adducts formed by toxic alkaloids by nano-scale liquid chromatography with mass spectrometry” J. Mass Spectrom. 2012, 47, 1303-1312

2011
Corresponding author
(74) Wu, Z.-H. and Tseng, W.-L.* “Combined cloud point extraction and Tween 20- stabilized gold nanoparticles for colorimetric assay of silver nanoparticles in environmental water” Anal. Methods, 2011, 3, 2915-2920.

(73)* Lin, Y.-H. and Tseng, W.-L.* "Fluorescence detection of coralyne and polyadenylation reaction using an oligonucleotide-based fluorogenic probe" Chem. Commun. 2011, 47, 11134-11136.

(72) Liu, C.H. and Tseng, W.-L.* "Oxidase-functionalized Fe3O4 nanoparticles for fluorescence sensing of specific substrate" Anal. Chim. Acta 2011, 703, 87- 93

(71) Lai, Y.-J. and Tseng, W.-L.* “Role of 5-thio-(2-nitrobenzoic acid)-capped goldnanoparticles in the sensing of chromium(VI): remover and sensor” Analyst 2011, 136, 2712-2717 (Back cover)

(70) Liu, F-C., Shen, C.-C. and Tseng, W.-L.* “The composites of cationic polyelectrolyte and glutathione-capped quantum dots for selective fluorescence detection of Cu2+” J. Chin. Chem. Soc. 2011, 58, 707-713

(69) Liu, C.-Y. and Tseng, W.-L.* “Colorimetric assay of cyanide and cyanogenic glycoside using polysorbate 40-stabilized gold nanoparticles” Chem. Commun.” 2011, 47, 2550-2552

2010
Corresponding author
(68) Lin, J.-H., Wu, Z.-H. and Tseng, W.-L.*“Extraction of environmental pollutants using magnetic nanomaterial” Anal. Methods, 2010, 2, 1874–1879 (invited review, front cover)

(67) Chang, C.-W., Chu, S.-P. and Tseng, W.-L.* “11-mercaptoundecanoic acid-capped gold nanoparticles for the preconcentration of melamine in milk powder prior to capillary electrophoresis“ J. Chromatogr. A 2010, 1217, 7800-7806

(66)* Lin, Y.-H. and Tseng, W.-L.* “Ultrasensitive Sensing of Hg2+ and CH3Hg+ “Based on the Fluorescence Quenching of Lysozyme Type VI-Stabilized Gold Nanoclusters” Anal. Chem. 2010, 82, 9194-9200.

(65) Lin, J.-H., Chang, C.-W., Wu, Z.-H. and Tseng, W.-L.* “Colorimetric Assay for S- Adenosylhomocysteine Hydrolase Activity and Inhibition Using Fluorosurfactant- Capped Gold Nanoparticles” Anal. Chem. 2010, 82, 8775-8779.

(64) Lin, C.-J., Liu, C.-H. and Tseng, W.-L.* ”Fluorescein isothiocyanate-capped gold nanoparticles for fluorescent detection of reactive oxygen species based on thiol oxidation and their application for sensing glucose in serum” Anal. Methods 2010, 2, 1810-1815.

(63) Yu, C.-J, Lin, C.-Y., Liu, C.-H., Cheng, T.-L. and Tseng, W.-L.* ”Synthesis of poly(diallyldimethylammonium chloride)-coated Fe3O4 nanoparticles for colorimetric sensing of glucose and selective extraction of thiol” Biosens. Bioelectron. 2010, 82, 913-917.

(62)* Lin, C.-Y., Yu, C.-J., Lin, Y.-H. and Tseng, W.-L.* ”Colorimetric Sensing of Silver(I) and Mercury(II) Ions Based on an Assembly of Tween 20-Stabilized Gold Nanoparticles” Anal. Chem. 2010, 82, 6830-6837. (Highly cited paper)

(61) Chang, C.-W., and Tseng, W.-L.* “Gold Nanoparticles Extraction Followed by Capillary Electrophoresis to Determine the Total, Free, Protein Bound Aminothiols in Plasma” Anal. Chem. 2010, 82, 2696-2702.

(60) Lin, J.-L., Chang, C.-W. and Tseng, W.-L. * “Fluorescent sensing of homocysteine in Urine: Using fluorosurfactant-capped gold nanoparticles and o- phthaldialdehyde” Analyst 2010, 135, 104-110 (inside cover)

(59) Huang, K.-W., Yu, C.-J. and Tseng, W.-L.* “Sensitivity Enhancement in the Colorimetric Detection of Lead(II) Ion Using Gallic Acid-Capped Gold Nanoparticles: Improving Size Distribution and Minimizing Interparticle Repulsion” Biosens. Bioelectron. 2010, 25, 984-989.

Non-corresponding author
(58) Yang, Y. H., Li, R. N., Tzou, S. C., Wang, J. Y., Lee, H. P., Wang, H. C., Chen, F. M., Wang, Y. H., Hsieh, M. C., Huang, M. Y., Tseng, W. L., Lin, S. R., Cheng, T. L. “Simultaneous Detection of Multiple Single-Nucleotide Polymorphisms by a Simple Membrane Chip” Genet. Test Mol. Biomarkers. 2010, 14, 653-659.

(57) W. C. Hung, W. L. Tseng, J. Shiea, H. C. Chang,* “Skp2 overexpression increases the expression of MMP-2 and MMP-9 and invasion of lung cancer cells.” Cancer Letters, 288, 156-161.

(56) K. H. Chuang, S. C. Tzou, T. C. Cheng, C. H. Kao, W. L. Tseng, J. Shiea, K. W. Liao, Y. M. Wang, Y. C. Chang, B. J. Huang, C. J. Wu, P. Y. Chu, S. R. Roffler,* and T. L. Cheng* “Measurement of Poly(ethylene glycol) by Cell-Based Anti- poly(ethylene glycol) ELISA” Anal. Chem. 2010 82, 2355–2362.

(55) Chuang, K.H., Wang, H. E., Cheng, T. C., Tzou, S. C., Tseng, W. L., Hung, W. C., Tai, M. H., Chang, T. K., Roffler, S. R., Cheng, T. L."Development of a universal anti- polyethylene glycol reporter gene for noninvasive imaging of PEGylated probes” J. Nucl. Med. 2010, 51, 933-941.

(54) Chuang, K. H., Wang, H. E., Chen, F. M., Tzou, S. C., Cheng, C. M., Chang, Y. C., Tseng, W. L., Shiea, J., Lin, S. R., Wang, J. Y., Chen, B. M., Roffler, S. R., Cheng, T. L. ”Endocytosis of PEGylated agents enhances cancer imaging and anticancer efficacy” Mol. Cancer Ther. 2010, 9, 1903-1912

2009
Corresponding author
(53) Lin, Y.-H. and and Tseng, W.-L.* “Highly sensitive and selective detection of silver ions and silver nanoparticles in aqueous solution using an oligonucleotide-based fluorogenic probe" Chem. Comm. 2009, 6619–6621

(52) Shen, C.-C. and Tseng, W.-L.* “A One-Step Synthesis of White-light-emitting Quantum Dots at Low Temperature ” Inorg. Chem. 2009, 48, 8689-8694.

(51) Chen, Y.-M., Cheng, T.-L. and Tseng, W.-L.* “Fluorescence Turn-On Detection of Iodide, Iodate and Total Iodine Using Fluorescein-5-Isothiocyanate-Modified Gold Nanoparticles” Analyst 2009, 134, 2106 – 2112.

(50) Li, M.-D., Tseng, W.-L.* and Cheng, T.-L. “Ultrasensitive detection of indoleamines by combination of nanoparticle-based extraction with capillary electrophoresis/laser-induced native fluorescence” J. Chromatogr. A 2009, 1216, 6451-6458.

(49) Yu, C.-J., Cheng, T.-L., and Tseng, W.-L.* “Effects of Mn2+ on Oligonucleotide- Gold Nanoparticle Hybrids for Colorimetric Sensing of Hg2+: Improving Colorimetric Sensitivity and Accelerating Color Change” Biosens. Bioelectron. 2009, 25, 204-210.

(48) Liu, F.-C., Chen, Y.-M., Lin, J.-H. and Tseng, W.-L.* “Synthesis of highly fluorescent glutathione-capped ZnxHg1xSe quantum dot and its application for sensing copper ion” Journal of Colloid and Interface Science 2009, 337, 414-419.

(47) Huang, C.-C. and Tseng, W.-L.* “Highly Selective Detection of Histidine Using o- Phthaldialdehyde Derivatization After the Removal of Aminothiols Through Tween 20-capped Gold Nanoparticles” Analyst 2009, 134, 1699-1705.

(46) Wu, H.-P., Yu, C-J., Lin, C.-Y., Lin, Y.-H. and Tseng, W.-L.* “Gold nanoparticles as assisted matrices for the detection of biomolecules in a high-salt solution through laser desorption/ionization mass spectrometry” J. Am. Soc. Mass Spectrom. 2009, 20, 875-882.

(45) Li, M.-D. Cheng, T.-L. and Tseng, W.-L.* “Nonionic Surfactant-Capped Gold Nanoparticles for Selective Enrichment of Aminothiols Prior to Capillary Electrophoresis with UV Absorption Detection” Electrophoresis 2009, 1, 388-395.

(44) Lin, C.-Y. and Tseng. W.-L. * “Selective Enrichment of Albumin in biological samples by Capillary Electrophoresis Using Segmental Filling with Sodium Octyl Sulfate in the Background Electrolyte” Electrophoresis 2009, 30, 1-8.

(43) Shen, C.-C., Tseng, W.-L.* and Hsieh, M.-M. “Selective enrichment of aminothiols using Tween 20-capped gold nanoparticles followed by capillary electrophoresis with laser-induced fluorescence” J. Chromatogr. A 2009, 1216, 288-293.

Non-Corresponding author
(42) Tseng, W.-L., Hsu, C.-Y., Wu, T.-H., Haung, S.-W., Hsieh, M.-M.* “Highly sensitive detection of chiral amino acids by capillary electrophoresis based on on- line stacking techniques” Electrophoresis 2009, 30, 2558-2564 (first author).

(41) Tzou, S.-C., Roffler, S., Chuang, K.-H., Yeh, H.-P., Kao, C.-H., Su, Y.-C., Cheng, C.-M., Tseng, W. L., Shiea, J., Cheng, K.-W., Tian-Lu Cheng, T.-L.* and Wang, H.-E. “Micro-PET imaging of -glucuronidase activity by the hydrophobic conversion of a glucuronide probe” Radiology, 2009, 252, 754-62

(40) Cheng, C.-M., Chu, P.-Y. Chuang, K.-H., Roffler, S. R. Kao, C.-H., Tseng, W.-L., Shiea, J., Chang, W.-D., Su, Y.-C., Chen, B.-M. Wang, Y.-M. and Cheng, T.-L.* “Hapten-derivatized nanoparticle targeting and imaging of gene expression by multimodality imaging systems” Cancer gene therapy. 2009, 16, 83-90.

2008
Corresponding author
(39) Yu, C.-J. and Tseng, W.-L. * “Colorimetric detection of mercury (II) in a high- salinity solution using gold nanoparticles capped with 3-mercaptopropionate acid and adenosine monophosphate” Langmuir 2008, 24, 12717-12722.

(38) Huang, C.-C. and Tseng, W.-L.* “Role of Fluorosurfactant-Modified Gold Nanoparticles in Selective Detection of Homcysteine Thiolactone: Remover and Sensor” Anal. Chem. 2008, 80, 6345-6350.

(37) Lin, C.-Y., Chang, H.-C., and Tseng. W.-L. * “Enrichment and separation of acidic and basic proteins using centrifugal ultrafiltration followed by polyelectrolyte- filled capillary electrophoresis” Electrophoresis 2008, 29, 3024-3031.

(36) Wu, H.-P., Huang, C.-C., Cheng, T.-L. and Tseng, W.-L.* ” Sodium hydroxide as pretreatment and fluorosurfactant-capped gold nanoparticles as sensor for the highly selective detection of cysteine” Talanta 2008, 76, 347-352.

(35) Chen, Y.-M., Yu, C.-J., Cheng, T.-L., and Tseng, W.-L.* “Colorimetric Detection of Lysozyme based on Electrostatic Interaction with Human Serum Albumin- Modified Gold Nanoparticles” Langmuir 2008, 24, 3654-3660. (corresponding author)

(34) Liu, F.-C., Cheng, T.-L., Shen, C.-C., Tseng, W.-L.,*, and Chiang, M. Y.* “Synthesis of Cysteine-Capped ZnxCd1-xSe Alloyed Quantum Dots Emitting in the Blue-Green Spectral Range” Langmuir 2008, 24, 2162-2167.

(33) Yu, C.-J., Chang, H.-C., and Tseng, W.-L. * “On-Line Concentration of Proteins by Sodium Dodecyl Sulfate-Capillary Gel Electrophoresis with Laser-Induced Native Fluorescence” Electrophoresis 2008, 29, 483-490.

Non-Corresponding author
(32) Tseng, W.-L., Chen, S.-M., Hsu, C.-Y. and Hsieh, M.-M.* “On-line concentration and separation of indolamines, catecholamines, and metanephrines in capillary electrophoresis using high concentration of poly(diallyldimethylammonium chloride)” Anal. Chim. Acta 2008, 613, 108-115.

(31) Shiea, J., Yuan, C. H., Huang, M. Z., Cheng, S. C., Ma, Y. L., Tseng, W. L., Chang, H. C., Huang, W. C. “Detection of native proteins ions in aqueous solution under ambient condition by electrospray laser desorption/ionization mass spectrometry” Anal. Chem. 2008, 80, 4845-4852.

2007
Corresponding author
(30) Hu, C.-C., Lin, J.-C., Tseng, W.-L.*, Huang, M. F., Chiu, T.-C. and Chang, H.-T.* “Analysis of Dynamic and Thermodynamic Adsorption of Nanoparticles on Solid Surfaces by Dark-field Light Scattering Measurements” J. Chin. Chem. Soc. 2007, 54, 869-878.

(29) Lin, C.-Y., Yu, C.-J., Chen, Y.-M., Chang, H.-C. and Tseng, W.-L.* “Simultaneous separation of anionic and cationic proteins by capillary electrophoresis using high concentration of poly(diallydimethylammonium chloride) as an additive” J. Chromatogr. A 2007, 1165, 219-225.

(28) Wu, H.-P., Su, C.-L., Hui-Chiu Chang and Tseng, W.-L.* “Sample-First Preparation: A Method for Surface-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry Analysis of Cyclic Oligosaccharides” Anal. Chem. 2007, 79, 1626- 1633.

(27) Wu, H.-P., Cheng, T.-L, Tseng, W.-L.* “Phosphate-Modified TiO2 Nanoparticles for Selective Detection of Dopamine, Levodopa, Adrenaline, and Catechol Based on Fluorescence Quenching” Langmuir 2007, 23, 7880-7885.

(26) Su, C. -L and Tseng, W. -L.* “Gold nanoparticles as Assisted Matrix for Determining Neutral Small Carbohydrates through Laser Desorption/Ionization Time-of-Flight Mass Spectrometry” Anal. Chem. 2007, 79, 1626-1633.

Non-Corresponding author
(25) Lee, K.-H., Huang, K.-M., Tseng, W.-L., Chiu, T.-C., Lin, Y.-W. and Chang, H.-T.* “Manipulation of the Growth of Gold and Silver Nanomaterials on Glass by Seeding Approach” Langmuir 2007, 23, 1435-1442.

2006
Corresponding author
(24) Su, C. -L and Tseng, W. -L.* “Selective Detection of Homocysteine under Alkaline Conditions” Rapid Commun. Mass Spectrom. 2006, 20, 3303-3308.

(23) Yu, C. -J. Su, C. -L and Tseng, W. -L.* “Separation of Acidic and Basic Proteins by Nanoparticle-Filled Capillary Electrophoresis” Anal. Chem. 2006, 78, 8004-8010.

(22) Yu, C. –J. and Tseng, W. –L.* “Online concentration and separation of basic proteins using cationic polyelectrolyte in the presence of reversed electroosmotic flow” Electrophoresis 2006, 27, 3569-3577.

(21) Lin, Y. -W., Tseng, W. -L.* and Chang, H. -T.* “Using a Layer-by-Layer Assembly Technique to Fabricate Multiply Colored Films of CdSe@CdS and CdTe Quantum Dots” Adv. Mater. 2006, 18, 1381-1386.

Non-Corresponding author
(20) Hsieh, M. -M., Chiu, T. -C., Tseng, W. -L. and Chang, H. -T.* “Electrophoretic analysis of biomolecules in microchannels using polymer solutions” Current Anal. Chem. 2006, 2, 17-33.

(19) Huang, Y. -F., Hsieh, M. -M., Tseng, W. -L., and Chang, H. -T.* “On-line concentration of microheterogeneous proteins by capillary electrophoresis using SDS and PEO as additives” J. Proteome Res. 2006, 5, 429-436.

2005 (After Ph. D)
(18) Tseng, W. -L., Lee, K. -H. and Chang, H. -T. “Using Nile Red-adsorbed gold nanoparticles to locate glutathione within erythrocytes ” Lamgunir. 2005, 21, 10676- 10683.

(19) Tseng, W. -L., Huang, M. -F., Huang, Y. -F. and Chang, H. -T. “Nanoparticle-filled capillary electrophoresis for the separation of long DNA molecules in the presence of hydrodynamic and electrokinetic forces” Electrophoresis 2005, 26, 3069-3075.

(18) Sreedhar, M., Lin, Y. -W., Tseng, W. -L. and Chang, H. -T. “Determination of amplified amines based on pH junction in capillary-electrophoresis with electrochemiluminescence detection” Electrophoresis 2005, 26, 2984-2990.

(17) Yang, Z., Lin, Y. -W., Tseng, W. -L., and Chang, H. -T. “Impacts that pH and metal ion concentration have on the synthesis of bimetallic and trimetallic nanorods from gold seeds” J. Materials Chemistry 2005, 15, 1-6.

(16) Chang, S. Y., Tseng, W. -L., Sreedhar, M. and Chang, H. -T. “Determination of small phosphorous-containing compounds by capillary electrophoresis” Talanta 2005, 66, 411-421.

2002 (Ph. D)
(15) Wang, S. -J., Tseng, W. -L., Lin, Y. -W.and Chang, H. -T. “On-line Concentration of Trace Proteins by pH Junctions in Capillary Electrophoresis with UV absorption Detection” J. Chromatogr. A 2002, 979, 261-270.

(14) Tseng, W. -L., Lin, Y. -W. and Chang, H. -T. “Improved Separation of Microheterogeneities and Isoforms of Proteins by Capillary Electrophoresis Using Segmental Filling with SDS and PEO in Background Electrolyte” Anal. Chem. 2002, 74, 4828-4834.

(13) Tseng, W. -L., Lin, Y. -W., Chen, K. -C. and Chang, H. -T. “Electrophoretic Separations of DNA in Bubble-Shape Microchannels” Electrophoresis 2002, 23, 2477-2484.

(12) Hsieh, M. -M., Hsu, C. -E., Tseng, W. -L. and Chang, H. -T. “Amplification of Small Analytes in Polymer Solution by Capillary Electrophoresis” Electrophoresis 2002, 23, 1633-1641.

(11) Tseng, W. -L., Chang, H. -T., Hsu, S. -M., Chen, R. -J. and Lin, S. “Immunoaffinity Capillary Electrophoresis:Determination of Affinity and Stoichiometry For Antibody-antigen Interaction Kinetics” Electrophoresis 2002, 23, 836-846.

2001 (Ph. D)
(10) Tseng, W. -L., Chiu, T. -C., Weng, J. -M. and Chang, H. -T. “Analysis of Albumins Using Albumin Blue 580 by Capillary Electrophoresis and Laser-Induced Fluorescence” J. Liq. Chromatogr. & Rel. Technol. 2001, 24, 2971-2982.

(9) Tseng, W. -L., Hsieh, M. -M., Wang, S. -J., Huang, C. -C., Lin, Y. -C., Chang, P. -L. and Chang, H. -T. “Analysis of Large-Volume DNA markers and PCR Products by Capillary Electrophoresis in the Presence of Electroosmotic Flow” J. Chromatogr. A 2001, 927, 179-190.

(8) Tseng, W. -L. and Chang, H. -T. “Regulation of Electroosmotic Flow and Electrophoretic Mobility of Proteins for Concentration Without Desalting” J. Chromatogr. A 2001, 924, 93-101.

(7) Huang, M. -F., Hsu, C. -E., Tseng, W. -L., Lin, Y. -C., and Chang, H. -T. “Separation of dsDNA in the Presence of Electroosmotic Flow under discontinuous conditions” Electrophoresis 2001, 22, 2281-2290.

(6) Tseng, W. -L. and Chang, H. -T. “A New Strategy for Optimizing Sensitivity, Speed, and Resolution in Capillary Electrophoretic Separation of DNA” Electrophoresis 2001, 22, 763-770.

2000 (Ph. D)
(5) Tseng, W. -L., Hsieh, M. -M., Wang, S. -J. and Chang, H. -T. “Effect of Ionic Strength, pH, and Polymer Concentration on the Separations of DNA Fragments in the Presence of Electroosmotic Flow” J. Chromatogr. A 2000, 894, 219-230.

(4) Tseng, W. -L. and Chang, H. -T. “On-line Concentration and Separation of Proteins by Capillary Electrophoresis Using Polymer Solutions” Anal. Chem. 2000, 72, 4805-4811.

(3) Hsieh, M. -M.,Tseng, W. -L. and Chang, H. -T. “On-Column Preconcentration and Separation of DNA Fragments Using Polymer Solutions in the Presence of Electroosmotic Flow” Electrophoresis 2000, 21, 2904-2910.

(2) Chang, H. -T., Chen, H. -S., Hsieh, M. -M. and Tseng, W. -L. “Electrophoretic Separation of DNA in the Presence of Electroosmotic Flow” Reviews in Anal. Chem. 2000, XIX, 45-74.

(1) Tseng, W.-L., Chiu, T.-C., Weng, J.-M. and Chang, H. -T. “Analysis of albumins using albumin blue 580 by capillary electrophoresis and laser-induced fluorescence” J. Liq. Chrom. & Rel. Technol. 2001, 24, 2971–2982.